IVF/ICSI Treatment

What is ICSI?

ICSI is a special technique in which a single sperm is injected into the centre of an egg after egg retrieval. The technique is commonly used when sperm count or motility is low (its ability to swim towards the egg). ICSI is also preferable for a number of reasons, for example combined with pre-implantation genetic diagnosis (PGD) or when sperm DNA fragmentation is high.

How Is ICSI Performed?

Intracytoplasmic sperm injection (ICSI) involves the direct injection of sperm into eggs obtained from the female partner.
In the laboratory, the embryologists will inject a single sperm into each egg.

There are five simple steps to ICSI:

  • After the femals egg reteival, the mature egg is held with a specialized pipette.
  • A single sperm is injected into the mature egg.
  • The needle is then carefully inserted through the shell of the egg and into the cytoplasm of the egg.
  • The sperm is injected into the cytoplasm.
  • The eggs are checked the following 24 hours for evidence a normal fertilization.

Once the ICSI is completed and fertilization is successful, it will then form into an embryo, the embryo transfer procedure is to place the embryo in the woman’s uterus.

How long does embryos take to develop?

The day after the sperm is injected into each egg, the embryologists will look for signs of fertilisation. The following day they will check to see if the embryo has cleaved. Embryos can be transferred at any stage from day 3 to day 6. By day day 3 the embryo will be a 6 or 8 cell embryo if they wait for day 5 embryos, the embryos should reach to a blastocyst stage.

The embryologists monitors and grades the embryos very carefully. In the majority of cases, if the embryos have developed well, they would not recommend more than 2 embryos to be transferred to reduce the risk of multiple pregnancy.

Embryos that are not transferred?

If you have left over good quality embryos that are not transferred on transfer day, they can be frozen. The embryos that are frozen can be stored for a long time for future transfer.

Is ICSI for me?

ICSI may be recommended when there is a reason to suspect that achieving fertilization may be difficult. ICSI is most often used with couples who are dealing with male infertility factors. Male infertility factors can include any of the following: low sperm counts, poor motility or movement of the sperm, poor sperm quality, sperm that lack the ability to penetrate an egg, or azoospermia.

Azoospermia is a condition where there is no sperm in the male’s ejaculation. There are two types of azoospermia: obstructive and non-obstructive.

We may recommend ICSI if:

  • The male partner has a very low sperm count
  • The male partner’s sperm has problems such as poor motility (not moving normally) or poor morphology (abnormal shape)
  • Previous attempts of concieving attempts have failed
  • Sperm needs to be collected surgically from the male’s testicles or epididymis, for instance if he’s had a vasectomy
  • You are using frozen sperm in your treatment
  • You are undergoing pre-implantation genetic diagnosis or screening




First step is to have recent hormone blood test and an antral follicle count scan on day 2 or 3 of the menstrale cycle...


IUI Treatment

Artifical insamination is a fertility treatment method. IUI treatment is suitable for patients upto the age of 34 years of age...


Egg Donation

Egg donation treatment option is suitable for women who can not achieve pregnancy using their own eggs for a variety of reasons...



Pre-Implantation Genetic Testing can be done to all IVF treatments. When PGD is done we do the 5 major genetic screaning of the embryo...


Egg Freezing

Egg freezing is for women who are not yet ready to have a child due to personal reasons but would like the opportunity at a future time in their life...


Sperm Donation

Sperm donation treatment program works very much like the IVF/ICSI treatment. The only difference is that instead of using the male partners sperm sample...


Cytoplasmic Transfer

Cytoplasmic transfer is the same as IVF/ICSI procedure in addition a young healthy donor eggs are used ...


Tandam Cycle

Tandam cycle is for women that have a low ovarian reserve. With the combination of donor eggs you will increase the percentage of pregnancy....


Embryo Donation

Embryo donation is a treatment option with a double donation aspect where the patients recieve both egg and sperm donation for when they are planning for their pregnancy...


Ovarian PRP Therapy

Ovarian PRP is a new and highly promising procedure without side affects. It is direct from the patients own blood sample...


Micro-Fluidic Chip Procedure

Sperm selection is a very important part of any infertility treatment. Being able to select the most viable and high motile sperm cells for fertilization...

Frequently Asked Questions

When a woman cannot carry her own pregnancy to term, some work with another woman who agrees to be a gestational surrogate. Specialists use IVF to make embryos with a woman’s eggs and her partner’s sperm. The surrogate is the one who goes through the pregnancy after IVF. But her DNA is not involved. The baby will be the biological child of both husband and wife.

Women who are over 40, have poor egg quality, or have not had success with previous cycles may consider an egg donor. This involves combining the man’s sperm with another woman’s donated eggs. If the procedure works, the woman becomes pregnant with a child who is biologically related to her partner but not herself.

Doctors will inject the sperm directly into the egg in a lab. This technique, called “ICSI” (intracytoplasmic sperm injection), helps when a man’s sperm count is very low or his sperm don’t move well. When the fertilized egg is ready, it goes into the woman’s uterus through the normal IVF process.

Fertile women can choose IUI using sperm from a donor. It may take several tries, but pregnancy rates are over 80%. You and your partner may want to see a counsellor first, to make sure you’re both ready to raise a child who is not biologically related to the father.

Intrauterine insemination (IUI) is a popular procedure for many fertility problems. Doctors place the man’s sperm into the woman’s uterus, but not into the egg itself, while she ovulates. You may also need to take drugs to prompt your body to ovulate. IUI is less expensive and simpler than IVF (in vitro fertilization), but pregnancy rates are much lower.

These include:

  • Low sperm count
  • Poor sperm movement
  • Misshaped sperm
  • Blocked sperm ducts

A few lifestyle changes can make a difference. If you smoke, quit. Smoking lowers fertility for men and women and dims pregnancy rates. In one study, men who stopped smoking saw their sperm counts climb 800%. Also, check your diet. Is it as healthy as possible? Ask your doctor about supplements. Some vitamins and

It has shown promise for many conditions. Now, some couples are trying this popular form of traditional Chinese medicine to address infertility. Research suggests it may improve sperm quality and blood flow to the uterus, help smooth out irregular ovulation, and boost IVF success rates.

Knowing your menstrual cycle improves your chances of getting pregnant. The first phase starts with the first day of your period or blood flow. Your body releases hormones that makes the eggs inside your ovaries grow. Between day 2 and 14, those hormones also help thicken the lining of your uterus to get ready for a fertilized egg. This is called the follicular stage.

The average menstrual cycle is 28-32 days. Ovulation usually happens between day 11 and 21 of your cycle. A hormone called luteinizing hormone (LH) surges, triggering the release of the egg that's ripest. At the same time, your cervical mucus becomes more slippery to help sperm make their way to the egg.

Generally, the highest chance of pregnancy is when sex happens1-2 days before ovulation. If you have a regular 28-day cycle, count back 14 days from when you expect your next period to start. Plan on having sex every other day around that time -- say, days 12 and 14.  Keep in mind that having sex every day may lower a man's sperm count. Your cycle may be longer or shorter, so an online ovulation calculator may help you identify the likely day.

After your body releases an egg, the hormone progesterone kicks in to help build and maintain the lining of the uterus. Progesterone causes your body temperature to go up slightly. So taking your temperature with a basal thermometer every morning before getting out of bed can help you figure out if you ovulated. These thermometers are available at the drugstore and are inexpensive, but they aren't as accurate as other methods for tracking ovulation.

A surge in LH triggers your ovaries to release the egg. The surge usually happens 36 hours before the egg is released. Ovulation kits check LH levels in your urine to help you pinpoint the day of ovulation. These kits, which are available at drugstores, are convenient and highly accurate. You may want to test 1-2 days before you expect the surge so you can note the rise in LH.

During the second half of your menstrual cycle, the hormone progesterone kicks in to help prepare the lining of your uterus for a fertilized egg. If the egg isn't fertilized and doesn't implant, it disintegrates, progesterone levels fall, and about 12 to 16 days later, the egg -- along with blood and tissues from the lining of the uterus -- is shed from the body. That process is menstruation. It usually lasts 3 to 7 days. Then the cycle begins again.

There is growing evidence that links environment to fertility. If you want to boost your chances of getting pregnant, you may want to:

  • Eat foods rich in folic acids.
  • Buy more organic foods and green products.
  • Avoid certain plastics (including plastic wrap).
  • Maintain a healthy body weight through diet and exercise.
  • Avoid alcohol and caffeine.

A study found that women whose body mass index (BMI) was above normal took twice as long to get pregnant as those with a normal BMI. If you're overweight or obese, losing weight can boost your fertility and chances of getting pregnant. According to the American Society for Reproductive Medicine, a drop in weight of 5%-10% can dramatically improve ovulation and pregnancy rates. Obesity can also cause infertility and low testosterone in men. Being significantly underweight can also lead to infertility.

Fertility goes down with age, especially after the mid-30s. It also lowers the chances that fertility treatments will be successful. Experts say you should talk to your doctor if you're under 35 and have been trying to conceive for more than 12 months, or over 35 and have been trying for more than 6 months.

Studies show that sperm count and sperm movement decrease as men age, as does sexual function. But there isn't a cut-off age that makes a man too old to father a child. One study found that it took men age 45 or older longer to get a woman pregnant once the couple started trying. If your partner is older, you may want to talk to your doctor about ways to boost your chances.

  • Manage stress.
  • Avoid alcohol and tobacco.
  • Maintain a proper weight.
  • Eat a diet high in zinc (found in meat, whole grains, seafood, and eggs), selenium (meat, seafood, mushroom, cereals, and Brazil nuts), and vitamin E. 
  • Keep the testicles cool -- no long, hot baths, hot tubs, or saunas, which can reduce the number of sperm.

TestimonialsSuccess Stories

Thank you so much..
Thank you so much for making my dreams of having a baby come true! Because of you Our experience in IVF treatment with you!! our treatment ws not stressfull. I am now 3 months pregnant and all is going well!! I am so happy to have contacted you.

Ally & Shane

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God Bless you all
Thank you so much to the team and doctor. They are professional, kind, caring and just overall amazing. They gave us hope, when we thought that our chances were very low. Our coordinator was there for us every step of the way, encouraging and supportive us, always answering all my questions and making us feel relaxed and to know that we are in good hands. My Partner and I are so grateful to the team. We now have a beautiful girl.

Janis & Terry

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I am PREGNANT!! :))
After 2 IVF attempts in 1 years and resulting in a negative result, I thought that I had no chance in falling pregnant....After having consultation with you, we decided to go with you and we are so happy to have picked you! The moment you started to assit me with all my questions and guiding me step by step on my treatment, I knew that we did the right thing. A special thanks to the doctor, he made it possible for us because I am ‘’PREGNANT!! :))


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I,m a mother!!
Which I thought it would not be possible... It would not have been possible without the great work of the doctor and the team. Thank you so so much for our dreams to come true....Thank you to the coordinator which was always there for me with all my questions and for guiding us step by step threw the treatment also the doctor that knows his work very well!!!

Nada & Josh

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You guys are amazing!
We can not thank you enough for our litte girl. The Doctor and the team are incredible...I had difficulty falling pregnant and thought that I would never have a child...Thank god I contacted you guys and made my dream come true......


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Cyprus IVF Babies
Şht. Erdoğan Yıldız Sokak No:5,
Kızılay, Nicosia / NORTH CYPRUS
Phone: +90 548 872 00 25
Email: [email protected]

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